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Examples of 4- dedimethylamino sancycline compounds with this R 7 substituent include 7-(4'-tolyl) 4- dedimethylamino sancycline. The primary outcome measure was the House–Brackmann grading system for facial-nerve function (see the Supplementary Appendix), 16 an easily administered, widely used clinical system for grading recovery from facial-nerve paralysis caused by damage to lower motor neurons.
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